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    Bcl-2 Mouse mAb
    EM1041
    規格: 價格:
    50μL ¥1280.00
    100μL ¥1980.00

    Overview

    Product name: Bcl-2 Mouse mAb
    Reactivity: Human, Rat, Mouse
    Alternative Names: B-Cell Leukemia/Lymphoma 2 ;B-Cell CLL/Lymphoma 2
    Source: Mouse
    Dilutions: WB 1:1,000-2,000 IHC 1:200 IF 1:100-200
    Immunogen: Synthetic Peptide
    Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
    Clonality: Monoclonal
    Isotype: IgG1
    Concentration: 1mg/mL
    Observed Band: 26kDa
    GeneID: 596
    Human Swiss-Prot No: P10415
    Cellular localization: Mitochondrion outer membrane,Nucleus membrane,Endoplasmic reticulum membrane
    Background: BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.
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